Version 3.0 is out as of August 1 2008. Improvements include the display of skyline plots (although I am still working on a manuscript on that) and many additional changes that should make running migrate a better experience.


For MacOS 10.5 users: I have created a new application migrateshell.app that sets up an environment that allows to run MIGRATE in parallel on multi-core machines without additional software installs

MIGRATE-N

estimation of population sizes

and gene flow using the coalescent

Migrate estimates effective population sizes and past migration rates between n population assuming a migration matrix model with asymmetric migration rates and different subpopulation sizes.
Migrate uses maximum likelihood or Bayesian inference to jointly estimate all parameters. The analysis can be constrained to subsets of migration patterns, such as setting some migration rates between populations to zero or constrain to symmetric rates or average over all migration rates, or use likelihood ratio tests and AIC values to compare different hypotheses. Migrate can use several different single or multilocus data types: sequence data using Felsenstein's 84 model with or without site rate variation, single nucleotide polymorphism data, microsatellite data using a stepwise mutation model or a brownian motion mutation model, and electrophoretic data using an 'k+1' allele model.
The output comes in two flavors: PDF and TEXT file. The file can contain:  Maximum likelihood: Estimates of all migration rates and all population sizes, assuming constant mutation rates among loci or a gamma distributed mutation rate among loci. Profile likelihood tables, Percentiles, Likelihood-ratio tests, and simple plots of the log-likelihood surfaces for all populations and all loci. (not all plots are implemented in the PDF, yet). Genealogy with best likelihood (Soon: printable through ET (eventtree -- http://popgen.scs.fsu.edu/Eventtree.html). Bayesian inference: Estimates of maximum posterior values of parameters and credibility intervals in table form, posterior distribution of parameters. Indications of convergence and effective sample size, presentation of frequency of migration events over time, genealogy with best likelihood printable through ET.Eventtree.htmlhttp://popgen.scs.fsu.edu/migabout.htmlshapeimage_2_link_0

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